Here's how it works:

* Anticodon: Each tRNA molecule carries a specific anticodon, a sequence of three nucleotides that is complementary to a specific codon on the mRNA molecule.

* Base pairing: The anticodon on the tRNA pairs with the codon on the mRNA through hydrogen bonding, which is a weak but specific interaction between complementary bases.

* Translation: This pairing allows the tRNA to bring the correct amino acid to the ribosome, where it is added to the growing polypeptide chain during protein synthesis.

Therefore, the interaction between tRNA and mRNA is based on the specific base pairing between their complementary sequences, facilitated by hydrogen bonds.