Here's a breakdown:
* Metaphase: Chromosomes line up along the center of the cell, attached to spindle fibers.
* Metaphase-anaphase transition: This is a crucial checkpoint where the cell ensures that all chromosomes are properly aligned and attached to the spindle fibers. This stage involves the activation of a protein complex called anaphase-promoting complex (APC). The APC triggers the breakdown of proteins holding sister chromatids together, allowing them to separate.
* Anaphase: Sister chromatids separate and move to opposite poles of the cell.
So, while it's technically not a separate stage with a unique name, the metaphase-anaphase transition is a critical step that initiates the separation of sister chromatids.
