1. Surface Area to Volume Ratio: As a cell grows larger, its volume increases at a faster rate than its surface area. This means the cell's membrane, which is responsible for nutrient uptake and waste removal, can't keep up with the demands of the increasing volume. Eventually, the cell wouldn't be able to efficiently exchange materials with its environment, leading to dysfunction.
2. DNA Overload: DNA contains the instructions for all cellular processes. If a cell grows too large, its DNA wouldn't be able to adequately control and regulate the increasing volume of cytoplasm and cellular activity. This can lead to errors in cellular processes and potentially uncontrolled growth (cancer).
Essentially, cell division ensures that a cell maintains an optimal surface area to volume ratio and prevents the DNA from being overloaded, allowing for efficient function and healthy growth.