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  • The Origin of B Cells: A History of Discovery and Naming
    B cells get their name because they were first discovered in the bursa of Fabricius, a lymphoid organ found in birds.

    Here's the breakdown:

    * Bursa of Fabricius: This organ is a specialized part of the bird's immune system, located in the cloaca (the common opening for the digestive, urinary, and reproductive systems).

    * Discovery: In the 1960s, scientists found that B cells were responsible for humoral immunity in birds, meaning they produced antibodies that circulated in the bloodstream. They traced the origin of these cells to the bursa of Fabricius.

    * Naming: Because of this discovery, the cells were named "B cells" to signify their origin.

    While humans and other mammals don't have a bursa of Fabricius, the equivalent organ in mammals is the bone marrow. It's in the bone marrow where B cells are produced and mature in humans. However, the name "B cell" has stuck even though the origin is different in mammals.

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