While they are primarily located in the stratum spinosum, they can also be found in the stratum basale to a lesser extent.
Here's a breakdown:
* Stratum spinosum: This is the main location of Langerhans cells. Their dendritic processes extend between keratinocytes, allowing them to monitor the surrounding environment.
* Stratum basale: A smaller number of Langerhans cells can be found in this layer, the deepest layer of the epidermis.
It's important to note: Langerhans cells are not present in all epidermal layers. They are primarily located in the stratum spinosum and to a lesser extent in the stratum basale.