Here's a breakdown of the process:

1. Proteins and enzymes: Lysosomal enzymes are synthesized in ribosomes and transported to the endoplasmic reticulum (ER).

2. ER to Golgi: From the ER, these enzymes move to the Golgi apparatus.

3. Sorting and packaging: Within the Golgi, the enzymes are sorted and packaged into vesicles within the TGN.

4. Budding: These vesicles bud off the TGN, becoming mature lysosomes.

The TGN acts as a crucial sorting station, ensuring that the specific enzymes destined for lysosomes are packaged correctly.