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  • MMP-9 and Connective Tissue Breakdown in Follicular Cells: A Detailed Explanation
    The enzyme responsible for the breakdown of connective tissue in follicular cells is matrix metalloproteinase (MMP), specifically MMP-9.

    Here's why:

    * Follicular cells are the cells surrounding the developing egg in the ovary. During ovulation, these cells need to break down to release the egg.

    * Connective tissue holds the follicular cells together.

    * MMPs are a family of enzymes that degrade the extracellular matrix, which includes connective tissue.

    * MMP-9 is specifically known to be involved in follicular rupture during ovulation. It breaks down the collagen and other proteins that hold the follicular cells together, allowing the egg to be released.

    It's important to note that other MMPs might also play a role, and the exact mechanisms involved in follicular rupture are still being studied. However, MMP-9 is a key player in this process.

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