During cytokinesis in a female, the cytoplasm and organelles are divided unequally between the two daughter cells. This unequal division is necessary to ensure that one daughter cell receives the inactive X chromosome (Xi). This process is known as X-inactivation and is important for gene dosage compensation in females. X-inactivation occurs during early embryonic development and results in the silencing of gene expression on one of the two X chromosomes in each female cell.