Antibiotics are not typically used to protect apples from fire blight. Instead, antibiotics are used to treat bacterial infections in humans and animals, and should only be used when prescribed by a healthcare provider. Antibiotics can have harmful effects on the native microbiome, which is why they should only be used when necessary.

The native microbiome of apples is a complex ecosystem of bacteria, fungi, and other microorganisms that live on the surface of the fruit. These microorganisms play an important role in protecting the apples from disease and spoilage. Antibiotics can disrupt the native microbiome, making the apples more susceptible to disease and spoilage.

In addition to disrupting the native microbiome, antibiotics can also have a negative impact on human health. Antibiotics can cause side effects such as nausea, vomiting, diarrhea, and rash. In rare cases, antibiotics can even cause death.

For these reasons, antibiotics should not be used to protect apples from fire blight. Instead, there are a number of other methods that can be used to control this disease, such as:

* Using resistant apple varieties

* Pruning infected branches

* Applying bactericides

* Using biological control agents

These methods are more effective at controlling fire blight and do not have the same negative effects on the native microbiome or human health.