While pufferfish is considered a delicacy in some parts of the world, it is important to note that it can be deadly if not prepared correctly. The toxicity of pufferfish comes from a substance called tetrodotoxin, which is found in the fish's liver, intestines, and reproductive organs. Tetrodotoxin is a powerful neurotoxin that can cause paralysis and respiratory failure, and even small amounts can be fatal.

Despite its potential danger, pufferfish is still consumed in certain countries, where it is prepared by specially trained chefs who are licensed to remove the toxic parts of the fish. The meat of the pufferfish is considered to be delicious, and it is often served as a sashimi dish. However, due to the risk of tetrodotoxin poisoning, it is strongly recommended to only consume pufferfish that has been prepared by a qualified chef.