Most research on EVs has focused on their role in human cells. However, a growing body of evidence suggests that EVs can also be released by non-human cells, and that they can play a role in communication between different species.
For example, one study showed that EVs released by the bacterium *Pseudomonas aeruginosa* can inhibit the growth of human lung cells. Another study showed that EVs released by the fungus *Candida albicans* can promote the growth of human breast cancer cells.
These studies suggest that EVs can be used by non-human cells to communicate with human cells, and that this communication can have a significant impact on human health.
The ability of EVs to deliver messages from non-human cells has important implications for our understanding of disease. For example, it is possible that EVs could be used to transmit infectious diseases between different species. It is also possible that EVs could be used to deliver therapeutic agents to specific cells in the body.
Further research is needed to investigate the role of EVs in communication between different species. This research could lead to new insights into the pathogenesis of disease and the development of new therapeutic strategies.