The ISS is a large, habitable artificial satellite in low Earth orbit, and it's the largest modular space station ever constructed. It's a collaborative project between multiple countries, including the United States, Russia, Japan, Canada, and the European Space Agency.

Here's why it fits your description:

* Man-made: The ISS is entirely built and assembled by humans.

* Laboratory: It's designed for scientific research in various fields like biology, physics, astronomy, and materials science.

* Orbiting Earth: The ISS continuously orbits Earth at an altitude of approximately 400 kilometers (250 miles).

While there have been other space stations in the past, the ISS is the only one currently in operation.