- BepiColombo (Launched in 2018, en route to Mercury)
- Cassini-Huygens (Launched in 1997, orbited Saturn from 2004 to 2017)
- Chandra (Launched in 1999, X-ray observatory in Earth's orbit)
- Dawn (Launched in 2007, orbited Vesta and Ceres from 2011 to 2018)
- GOES (Geostationary Operational Environmental Satellites, weather and climate monitoring)
- Hubble (Launched in 1990, optical and ultraviolet telescope in Earth's orbit)
- Insight (Launched in 2018, studying the interior of Mars)
- Juno (Launched in 2011, studying Jupiter's interior and atmosphere)
- MESSENGER (Launched in 2004, orbited Mercury from 2011 to 2015)
- New Horizons (Launched in 2006, flew by Pluto in 2015, currently exploring the Kuiper Belt)
- OSIRIS-REx (Launched in 2016, studying the asteroid Bennu and returning a sample to Earth)
- Parker Solar Probe (Launched in 2018, studying the Sun's atmosphere and attempting to touch its corona)
- Solar Orbiter (Launched in 2020, studying the Sun's polar regions and magnetism)
- SOFIA (Stratospheric Observatory for Infrared Astronomy, airborne telescope)
- TESS (Transiting Exoplanet Survey Satellite, searching for exoplanets orbiting bright stars)
- Voyager 1 and 2 (Launched in 1977, traveling through interstellar space)
_Note that this list might not be exhaustive, and some space probes may have ceased operations or been decommissioned since the last update._